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- ArticleJeffery JR, Downs A, Grahame JW, Lye C, Ramsey E, Thomson AE.Transplantation. 1978 Jun;25(6):287-9.In a randomized study ww have been unable to demonstrate any beneficial effect of cadaver donor pretreatment with 5 g of methylprednisolone and 7 g of cyclophosphamide on graft function or survival in 22 recipients of pretreated kidneys compared with 30 recipients of nonpretreated kidneys.